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Search Results for " bms 354825 "

6

Compounds

Cat No. Product Name Synonyms Targets
T1448L Dasatinib monohydrate BMS-354825 Monohydrate Apoptosis , Bcr-Abl , Src , c-Kit , Ephrin Receptor , Autophagy
Dasatinib monohydrate (BMS-354825 Monohydrate) is an orally bioavailable synthetic small molecule-inhibitor of SRC-family protein-tyrosine kinases. Dasatinib monohydrate binds to and inhibits the growth-promoting activit...
T18750 N-Deshydroxyethyl Dasatinib N-Deshydroxyethyl BMS-354825 Others , IAP , Drug Metabolite
N-Deshydroxyethyl Dasatinib (N-Deshydroxyethyl BMS-354825) is a metabolite of Dasatinib, a dasatinib-based molecule that degrades ABL by binding to the IAP ligand via a linker to form SNIPER.N-Deshydroxyethyl Dasatinib i...
T22303 Dasatinib hydrochloride BMS-354825 HCl Bcr-Abl , Src , c-Kit
Dasatinib hydrochloride (BMS-354825 HCl) (BMS-354825) hydrochloride is a highly potent, ATP competitive, orally active dual Src/Bcr-Abl inhibitor with potent antitumor activity. The Kis are 16 pM and 30 pM for Src and Bc...
T1448 Dasatinib BMS-354825 Apoptosis , Bcr-Abl , Src , c-Kit , Autophagy
Dasatinib (BMS-354825) is a tyrosine kinase inhibitor that inhibits Src and Bcr-Abl (Ki=16/30 pM) and is orally active and ATP-competitive. Dasatinib has antitumor activity and is used in the treatment of leukemia and ly...
T18595 Dasatinib carbaldehyde PROTAC ABL binding moiety 4,BMS-354825 carbaldehyde Others , Ligands for Target Protein for PROTAC
Dasatinib carbaldehyde (PROTAC ABL binding moiety 4) is based on Dasatinib which is an ABL inhibitor, binds to the IAP ligand via a linker, and forms SNIPER [1].
T10962 Dasatinib-d8 BMS-354825 D8 Others
Dasatinib D8 is deuterium-labeled dasatinib. Dasatinib is a dual Bcr-Abl and Src family tyrosine kinase inhibitor.
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